ABSTRACT
This study was performed to investigate Apolipoprotein E phenotypes and the relationship among lipid levels, nutrient intakes, lifestyles and risk factors between subjects with and without hyperlipidemic risk. The data were collected from 675 industrial male workers who had completed annual medical examination. Compared to the normal group, the hyperlipidemic risk group in Apo E3 and E4 had significantly higher BMI (p < 0.05) and showed significantly higher body fat (%), waist circumference and WHR in all types of Apo E (p < 0.05). In addition, the hyperlipidemic risk group had significantly higher total cholesterol, LDL-cholesterol, triglyceride and AI than the normal group in all types of Apo E (p < 0.05). Intakes of protein, calcium, phosphorus, iron, vitamin A, vitamin B1, vitamin B2, vitamin C and niacin in Apo E3 were significantly lower in the hyperlipidemic risk group than in the normal group (p < 0.05). In the logistic regression analysis, after adjustment for other factors, Apo E2 + E4, waist and WHR were the significant risk factors associated with hyperlipidemia, but protein intakes were associated with significantly lower risks of hyperlipidemia (p < 0.05). In conclusion, genetic factor (Apo E2 or Apo E4), anthropometric index and nutrient intake seem to influence hyperlidemic risk. Further studies and efforts will be needed to evaluate the independent relationships among hyperlipidemic risk factors.
Subject(s)
Humans , Male , Adipose Tissue , Apolipoprotein E2 , Apolipoprotein E3 , Apolipoproteins , Apolipoproteins E , Ascorbic Acid , Calcium , Cholesterol , Hyperlipidemias , Iron , Life Style , Logistic Models , Niacin , Phenotype , Phosphorus , Riboflavin , Risk Factors , Thiamine , Vitamin A , Waist CircumferenceABSTRACT
Nutritional rickets, which is caused by deficiency of calcium or vitamin D, is a rare disease in developed countries. However some cases have been reported recently, that developed as a result of a restricted and nutritionally imbalanced diet due to atopic dermatitis and related food allergy. We treated two infant cases of nutritional rickets. The infants had suffered from atopic dermatitis, and were fed "Sun-sik" (a powdery mixture of several grains and fruits) without receiving cow's milk or any milk products in their diet. After an adequate supply of calcium and nutritional management, they were markedly improved.
Subject(s)
Humans , Infant , Calcium , Edible Grain , Dermatitis, Atopic , Developed Countries , Diet , Food Hypersensitivity , Milk , Rare Diseases , Rickets , Vitamin DABSTRACT
Coronary artery fistula (CAF) is a rare congenital cardiac anomaly, which mainly drains to the right side heart. As the progression to spontaneous closure in CAF was rare, it needed surgery or catheteric embolization in asymptomatic patients due to the future risk of congestive heart failure, myocardiac infarction or sudden death. With the advent of high resolution two-dimensional and color doppler echocardiography during the past decade, more cases of CAF have been diagnosed and spontaneously closed cases have been increased. Here we report a healthy neonate except heart murmur, who showed a right coronary to left ventricle fistula with progression to spontaneous closure at 11months of age. As the natural course of CAF is still poorly defined and spontaneous closure is increasing, it will be desirable to be followed up regularly by echocardiography in asymptomatic cases, rather than to be corrected surgically.